L-Tryptophan

Brief Overview:
L-Tryptophan is an essential amino acid which important for growth and stress reducer. It also helps developing animal organs and optimalizing immune system. L-Tryptophan is commonly sythesized in the plants and microorganisms.
Manufacturing Process
L-tryptophan is produced by incubating a microbe capable of producing L-tryptophan and capable of constitutive expression of maleate synthase·isocitrate lyase·isocitrate dehydrogenase kinase/phosphatase operon in a culture medium so as to generate and accumulate L-tryptophan in the culture medium and harvesting the L-tryptophan. In commercial industry, Tryptophan is produced by biological synthetic based on fermentation process of serine and indole using either wild-type or genetically modified from bacteria such as B. amyloliquefaciens, B. subtilis, C. glutamicum or E. coli.